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Veterinary aspects were focused, showing the wide distribution of infection among animals. The cell-mediated immunity was better characterized, incorporating the recent findings. Serological methods for diagnosis were also compared for their parameters of accuracy, including the analysis of relapse.

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Clinical forms have been better classified in order to include the pictures less frequently observesiod. Itraconazole and the trimethoprim-sulfamethoxazole combination was compared regarding efficacy, effectiveness and safety, demonstrating that azole should be the first choice in the treatment of paracoccidioidomycosis. This is exactly what Open Access Journals provide and this is the reason why I support this endeavor.

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